Organization: Public Health Agency of Canada. News stories, speeches, letters and notices, Reports, analysis and official statistics, Data, Freedom of Information releases and corporate reports. on AstraZeneca COVID-19 vaccine for reports of very rare side effects. Neither Pfizer nor Moderna . 967 0 obj <>stream 0000006792 00000 n Excipients are the non-active ingredients that are added to the vaccine for a variety of reasons. Discard the vial and do not combine residual vaccine from multiple vials. 0000107012 00000 n AstraZeneca has updated the efficacy result of its coronavirus vaccine trial in the US, after health officials insisted they wanted to include the latest information. request information about a specific topic, United Kingdom Medicines & Healthcare products Regulatory Agency, University of Oxford Vaccine Knowledge Project, United States Centers for Disease Control and Prevention, A weakened adenovirus, which delivers the the COVID-19 spike glycoprotein (this is the active ingredient; also called the 'antigen'), L-histidine hydrochloride monohydrate (amino acid), Safety and immunogenicity of ChAdOx1 nCoV-19 vaccine administered in a prime-boost regimen in young and old adults (COV002): a single-blind, randomised, controlled, phase 2/3 trial (, A Novel Chimpanzee Adenovirus Vector with Low Human Seroprevalence: Improved Systems for Vector Derivation and Comparative Immunogenicity (, Adenoviral vectors are the new COVID-19 vaccine front-runners. But individuals may choose to delay vaccination for 3 months following the infection. We also use cookies set by other sites to help us deliver content from their services. The AstraZeneca vaccine is made from an adenovirus that has been changed in the lab so it can't cause harm. 2020 has been a difficult year for all, but has seen 58 vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) be developed and in clinical trials,1 with some vaccines reportedly having more than 90% efficacy against COVID-19 in clinical trials. Vaxzevria is a vaccine for preventing coronavirus disease 2019 (COVID-19) in people aged 18 years and older. %%EOF To help pregnant women make this assessment, they should be provided with Oxford-AstraZeneca COVID-19 vaccine efficacy. A third injection may be given at least 8 weeks after the second injection if advised by your doctor. We use some essential cookies to make this website work. Consumer Information. However, a causal relationship with the vaccine has neither been confirmed nor ruled out and more rigorous studies are needed to fully assess the significance of If you have had a blood clot occurring at the same time as having low levels of blood platelets (thrombosis with thrombocytopenia syndrome, TTS) after receiving the vaccine. For countries that have not yet achieved high vaccine coverage rates in the high-priority groups and that are experiencing high incidence of COVID-19 cases combined with vaccine supply constraints, longer intervals i.e. Talk to the healthcare provider if you have questions. Unit dose strength (s) > 0.7 1011 vp/mL. The recommended dosage is two doses given intramuscularly (0.5ml each) with an interval of 8 to 12 weeks. 0000018147 00000 n During use it can be stored from 2C to 25C. 0000004240 00000 n The expiry date refers to the last day of that month. 0000002960 00000 n Some cases had a fatal outcome. LqIai8O=,*EM~|>0: NiV|+'#M(FYQc`uic+)Gy1Q(:'4~0:,9Dbdf&. Article number: 33474. The benefits of booster vaccination are recognized following increasing evidence of waning vaccine effectiveness against mild and asymptomatic SARS-CoV-2 infection over time. 0000007190 00000 n 818 0 obj <> endobj As of May 2022, people over age 5 are eligible to receive an FDA-approved COVID-19 vaccine.For booster shots, the CDC recommendation is that you should be older than 5 years of age. Once it is approved for human research, there are three phases that take place before the vaccine can be considered for approval for public use. 8 dose multidose vial (4 ml) with rubber stopper and aluminium overseal in a pack of 10 vials. 803 0 obj <>/Filter/FlateDecode/ID[<2F70D35E7B8A59458B52A8ED8203A71C><24F7C9D4F005C249BEA4CA3B57A534AF>]/Index[779 189]/Info 778 0 R/Length 129/Prev 229930/Root 780 0 R/Size 968/Type/XRef/W[1 3 1]>>stream Some excipients are added to a vaccine for a specific purpose. On his way to a meeting to present . Nijmegen, 6545CG 0000055862 00000 n z(2$bW*; ! 0000007231 00000 n syndrome [GBS]), rapid swelling under the skin in areas such as the face, lips, mouth and throat (which may cause difficulty in swallowing or breathing) (angioedema), capillary leak syndrome (a condition causing fluid leakage from small blood vessels), very low levels of blood platelets (immune thrombocytopenia) that can be associated with bleeding (see section 2, Blood disorders), blood clots in the brain, not associated with low level of blood platelets (see section 2, Blood disorders), inflammation of the spinal cord which may cause muscle weakness, localised or radiating back pain, bladder and bowel symptoms and changes in sensation (transverse myelitis). Older people have been prioritized to receive COVID-19 vaccines in many areas of the world. Results from a large clinical trial in the United States and South America indicate that AstraZeneca's COVID-19 vaccine, AZD1222, is well-tolerated and protects against symptomatic COVID-19 disease, including severe disease or hospitalization. 0000002028 00000 n 0000003715 00000 n The majority of these cases occurred within the first 3 weeks following vaccination but some have also been reported after this period. 569 0 obj <>/Filter/FlateDecode/ID[<422DFA914F61AD45909E39C193482A39>]/Index[548 34]/Info 547 0 R/Length 105/Prev 177378/Root 549 0 R/Size 582/Type/XRef/W[1 3 1]>>stream 3. The AstraZeneca vaccine does contain polysorbate. %PDF-1.7 By reporting side effects you can help provide more information on the safety of this vaccine. You will receive 2 injections. It uses a dead version of the SARS -CoV-2 virus so that it cannot replicate, but it keeps the surface spike protein intact to trigger the body's immune system. The AstraZeneca vaccine is based on an adenovirus that circulates in chimpanzees . COVID-19 Vaccine AstraZeneca is a vaccine used for preventing COVID 19, caused by a virus called coronavirus (SARS-CoV-2). Such reactions may include a combination of any of the following symptoms: In clinical studies with the vaccine, fewer side effects were reported after the second dose and those that were reported were milder in nature when compared to after the first dose. Treatment for: Prevention of COVID-19. Six of the 28 died from their clotting complications. 0000002358 00000 n Read all of this leaflet carefully before the vaccine is given because it contains important information for you. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. % Surfactants (also called 'emulsifiers') are excipients that can help make sure ingredients like oil and water stay together during the transportation and storage process. This type of vaccine development technology has been tested for many other diseases such as influenza (flu) and Middle East respiratory syndrome coronavirus (MERS-CoV). Some affected patients had a previous diagnosis of CLS. Last updated by Judith Stewart, BPharm on Feb 15, 2021. Solution for injection. Stabilizers, like L-histidine or sucrose, make sure the vaccine is able to stay effective during the times it is transported and stored.. After the first dose is withdrawn, the vaccine should be used as soon as practically possible and within 6 hours. 71 0 obj <> endobj 97 0 obj <>/Filter/FlateDecode/ID[(g\344kPbb\247F\260\2010\356\240|\314\024) (g\344kPbb\247F\260\2010\356\240|\314\024)]/Index[71 27]/Info 69 0 R/Length 82/Prev 165766/Root 72 0 R/Size 98/Type/XRef/W[1 3 1]>> stream In the meantime, we must maintain and strengthen public health and social measures that work: masking, physical distancing, handwashing, respiratory and cough hygiene, avoiding crowds, and ensuring good ventilation. The Oxford-AstraZeneca vaccine is cheaper and easier to transport and store than some of the other vaccines approved for use to date and as such, was going to play a key part in combating the . If you experience any of the following from around 4 days after vaccination you should seek medical advice urgently: Tell your doctor, pharmacist or nurse if you experienced a blood clot occurring at the same time as low levels of platelets after receiving a previous dose of the vaccine. 4 to 12 weeks. 0000019840 00000 n [recombinant]) [COVID-19 Vaccine AstraZeneca] with other vaccines have not been evaluated. 0000054208 00000 n The final stage (Phase III) provides the vaccine to thousands of people from the target population to see how safe and effective it is. (Centers for Disease Control and Prevention). "A Simple Breakdown of the Ingredients in the COVID Vaccines." 11 Jan 2021. 0000004761 00000 n No serious adverse events were reported with AZD1222, and reactions were lessened with the use of prophylactic paracetamol. The AstraZeneca vaccine is based on time-tested technology that employs a harmless cold virus (called adenovirus) that has been genetically modified to stimulate an immune response against the coronavirus. The last nine ingredients on the list are called 'excipients.' 0000053643 00000 n The majority of these cases occurred within the first four weeks following vaccination. Moderna COVID-19 vaccine. AZD1222 works by using a viral vector (ChAdOx1 - chimpanzee adenovirus Oxford 1) based on a weakened version of a common cold (adenovirus) virus that contains the genetic material of the SARS-CoV-2 virus spike protein. This includes any possible side effects not listed in this leaflet. 0000025064 00000 n FDA Approved: No This will help to protect you against COVID-19 in the future. Tell your doctor, pharmacist or nurse if you are taking, have recently taken or might take, any other medicines or vaccines. Success! It causes the body to produce its own protection (antibodies) against the virus. Preliminary findings highlight the urgent need for a coordinated approach for surveillance and evaluation of variants and their potential impact on vaccine effectiveness. If you have ever had a severe allergic reaction after any other vaccine injection or after you were given COVID-19 Vaccine AstraZeneca in the past. a severe headache that is not relieved with simple painkillers or is getting worse or feels worse when you lie down or bend over, an unusual headache that may be accompanied by blurred vision, confusion, difficulty with speech, weakness, drowsiness or seizures (fits), rash that looks like small bruises or bleeding under the skin beyond the injection site, or any unexplained bleeding. The Astra Zeneca vaccine remains a suitable option as a heterologous booster to primary series vaccination with a different vaccine. The Oxford-AstraZeneca vaccine contains no common food allergens such as milk, wheat, egg, peanuts, tree nuts, or shellfish, or their by-products. Authors Maria Deloria Knoll 1 , Chizoba Wonodi 2 Affiliations 1 Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, 21231 USA. <>stream information about the risks of COVID-19 in pregnancy, the likely benefits of vaccination in the local epidemiological context, and the current limitations of safety data in pregnant women. WHO recommends the use of the ChAdOx1-S [recombinant] COVID-19 vaccine in pregnant women only when the benefits of vaccination to the pregnant woman outweigh the potential risks. 56 0 obj It will take only 2 minutes to fill in. However, maintaining a homologous schedule is still acceptable. This medicine contains less than 1 mmol sodium (23 mg) per dose of 0.5 ml. The results confirmed a single dose of AZD1222 resulted in a four-fold increase in antibodies to the SARS-CoV-2 virus spike protein in 95% of participants one month after injection. 0000097826 00000 n $x >HdA@; 0000011249 00000 n << /Linearized 1 /L 149707 /H [ 2229 301 ] /O 59 /E 79897 /N 11 /T 149221 >> The Janssen COVID-19 Vaccine includes the following ingredients: recombinant, replication-incompetent adenovirus type 26 expressing the SARS -CoV-2 spike protein, citric acid s/s's?3on1;XX(@?<=f@(tv4;r% ~IX This included some severe cases with blood clots in different or unusual locations and excessive clotting or bleeding throughout the body. For the Oxford-AstraZeneca vaccine, 30 cases of anaphylaxis have been confirmed . It is not yet known how long you will be protected for. 0000015573 00000 n 4.2 Posology and method of administration Posology Individuals 18 years of age and older The COVID-19 Vaccine AstraZeneca vaccination course consists of two separate doses of 0.5 ml each. The solution is colourless to slightly brown, clear to slightly opaque. /ID [<46442D36362D36432D33412D43412D36>] "Similar to the flu vaccine, the side effects are pretty mild, and the most common one is fatigue," says Malaty . Once this enters the body, it tells your cells to make copies of the spike protein. "It can't give you an infection. This publication is licensed under the terms of the Open Government Licence v3.0 except where otherwise stated. AstraZeneca's active ingredient is a non-infectious chimpanzee adenovirus, which Professor Pouton described as a "delivery system" for a DNA payload, which contains code to produce the SARS-CoV-2 spike protein, into the body's cells. 0000097788 00000 n 0 If you miss a scheduled injection, you may not be fully protected against COVID-19. 0000015637 00000 n Your doctor, pharmacist or nurse is responsible for storing this vaccine and disposing of any unused product correctly. << /Type /XRef /Filter /FlateDecode /Length 115 /W [ 1 3 1 ] /Index [ 53 36 ] The AstraZeneca vaccine is not a live virus vaccine, it is therefore biologically and clinically unlikely to pose a risk to the breastfeeding child. 0000099076 00000 n 0000006590 00000 n Produced in genetically modified human embryonic kidney (HEK) 293 cells. What is the evidence for vaccine efficacy and safety in adults (18-59 years)? No substantive data are available related to impact of the vaccine on transmission or viral shedding. Getty Images. The first ingredient on the listthe weakened adenovirusis the active ingredient in this vaccine. Well send you a link to a feedback form. This information was provided by the drug's manufacturer when this drug product was approved for sale in Canada. JZD| The vaccine is not recommended for persons younger than 18 years of age pending the results of further studies. Read the 16 April 2021 statement of the WHO Global Advisory Committee on Vaccine Safety In the trial, 543 participants received AZD1222 (56 also received a prophylactic dose of the pain killer paracetamol), and 534 received MenACWY, a comparator meningococcal conjugate vaccine. AstraZeneca's vaccine contains a chimpanzee adenovirus genetically engineered to avoid its replication and instead make Covid spike protein in people receiving the jab. /Size 89 /Prev 149222 dose regimen of this vaccine is believed to be more protective against variants of concern than a single dose alone. 54 0 obj Information about the Moderna coronavirus vaccine, including a full list of ingredients and side effects, is available: Information on the Moderna COVID-19 vaccine. 0000004537 00000 n Title: Redirect for COVID-19 AstraZeneca Vaccine EUA Fact Sheet for Recipients Author: CDC/NCIRD Subject: When these blood clots do occur, they may be in unusual or atypical locations (e.g. xVN@}W#E{I HTJB+!`)m;:KQyX99se 0000000016 00000 n In . 0000004648 00000 n The need for, and timing of, booster doses for children aged 5-11 years has not yet been determined. You may access the guidance document here. EDTA is not listed as an ingredient in the Johnson &. There are limited data on the use of COVID-19 Vaccine AstraZeneca in pregnant or breastfeeding women. 0000002484 00000 n Vaxzevria is made up of another virus (of the adenovirus family) that has been modified to contain the gene for making a protein from SARS-CoV-2, the virus that causes COVID-19. The AstraZeneca vaccine uses a harmless, weakened animal virus (called a viral vector) that contains the genetic code for the coronavirus spike protein. startxref AstraZeneca-Oxford vaccine was 76% effective at preventing symptomatic COVID-19 two weeks after the second dose and was 100% effective in stopping severe disease and hospitalization in a. When COVID-19 Vaccine AstraZeneca is given for the first injection, the second injection to complete the vaccination course should also be with COVID-19 Vaccine AstraZeneca. This type of vaccine technology has been tested for many other diseases such as influenza (flu) and middle east respiratory . endstream endobj 347 0 obj <>/Metadata 343 0 R/Outlines 30 0 R/OutputIntents[<>]/Pages 342 0 R/StructTreeRoot 38 0 R/Type/Catalog>> endobj 348 0 obj <>/Font<>>>/Fields[]>> endobj 349 0 obj <. 0000103016 00000 n See the end of section 4 for how to report side effects. endstream endobj startxref 0 %%EOF 72 0 obj <>>> endobj 95 0 obj <> stream Vaccine efficacy tended to be higher when the interval between doses was longer. None of the ingredients in this vaccine can cause COVID-19. Contact your doctor or healthcare professional immediately or go to the nearest hospital emergency room right away if you have an allergic reaction. Adenoviruses are a common group of viruses that cause different types of sicknesses like bronchitis. Wait until any effects of the vaccine have worn off before you drive or use machines. The Council for International Organizations of Medical Sciences classifies rates of adverse events or medicines and vaccines as follows: The AstraZeneca vaccine has an efficacy of 72% against symptomatic SARS-CoV-2 infection, as shown by the primary analysis of data irrespective of interdose interval from trial participants who received 2 standard doses with an interval varying from about LYpeP4 &=C&CBzLL3y20gah!A '1>ederj4+e@Zg Rc`TaPa`2R6r G2p T endstream endobj 549 0 obj <. If you get any side effects, talk to your doctor, pharmacist or nurse. This is the same type of vaccine that flu and the Middle East Respiratory Syndrome vaccines have used for years. 0000005556 00000 n 3.What if I am taking, have recently taken or might take other medicinesor Function. Possible side effects 5. 0000004762 00000 n You can help by reporting any side effects you may get. Guillain-Barr syndrome (GBS) has been reported very rarely following vaccination. Keep this medicine out of the sight and reach of children. A full list of ingredients for the qualitative and quantitative composition of the vaccine and a full list of the excipient composition of the vaccine can be found at point 6 in the Summary. 0000009880 00000 n The Oxford-AstraZeneca vaccine contains no pork products or by-products. 0000007733 00000 n Interim results were published in. 0000001605 00000 n The AstraZeneca vaccine remains a safe and effective choice to protect against COVID-19, and will protect against severe outcomes from getting infected with COVID-19, including illness, hospitalization and death. %%EOF &Va(f+0&+FIcDHoL O'`` r/ RV"Lj~=n%8w?C * 10 dose multidose vial (5 ml) with rubber stopper and aluminium overseal in a pack of 10 vials. SAGE accepts two heterologous doses of WHO EUL COVID-19 vaccines as a complete primary series. This means that a COVID-19 vaccine cannot make you sick with COVID-19. If side effects such as pain and/or fever are troublesome, medicines containing paracetamol can be taken. , ,p Published March 31, 2021 Updated Aug. 1, 2021. py]IioB^;+q/u_q^okl@ 0s7(-e?rbBS\Lg!-,p77cicd@&( However, a mild fever or infection, like a cold, are not reasons to delay vaccination; If you have ever had a condition known as heparin-induced thrombocytopenia and thrombosis (HITT or HIT type 2), or a blood clot in the sinus veins in the brain; If you have a problem with bleeding or bruising, or if you are taking a blood thinning medicine (anticoagulant); If your immune system does not work properly (immunodeficiency) or you are taking medicines that weaken the immune system (such as high-dose corticosteroids, immunosuppressants or cancer medicines). 4 ml ) with an interval of 8 to 12 weeks healthcare provider if have... Vaccine is based on an adenovirus that circulates in chimpanzees still acceptable sodium ( mg! Antibodies ) against the virus worn off before you drive or use machines of rare. Room right away if you have an allergic reaction product was Approved for sale in Canada complete series! The terms of the vaccine on transmission or viral shedding this leaflet pain and/or fever are troublesome, medicines paracetamol... In the COVID Vaccines. & quot ; it can & # x27 ; s manufacturer when drug... Except where otherwise stated booster vaccination are recognized following increasing evidence of vaccine..., diagnosis or treatment changed in the Johnson & amp ; vaccine from multiple vials a pack of vials. No pork products or by-products findings highlight the urgent need for, and reactions were lessened the. The world as a complete primary series n Produced in genetically modified human embryonic kidney ( HEK ) 293.... ; a Simple Breakdown of the vaccine is believed to be more protective against variants of concern a. Interval of 8 to 12 weeks when this drug product was Approved for sale in Canada be fully protected COVID-19... Of sicknesses like bronchitis a third injection may be given at least 8 weeks after second! Diagnosis or treatment Johnson & amp ; ingredient in this leaflet educational purposes only and is not yet known long. /Size 89 /Prev 149222 dose regimen of this vaccine because it contains important information for you sites to help deliver... Recognized following increasing evidence of waning vaccine effectiveness different vaccine by Judith Stewart, BPharm Feb! Many other diseases such as influenza ( flu ) and middle east respiratory group of viruses that cause types! Product correctly we use some essential cookies to make copies of the ingredients in the so! Cells to make copies of the Open Government Licence v3.0 except where otherwise.... Sage accepts two heterologous doses of WHO EUL COVID-19 vaccines in many areas of the spike protein to... N [ recombinant ] ) [ COVID-19 vaccine AstraZeneca in pregnant or breastfeeding women Read all of this leaflet before... Regimen of this vaccine can not make you sick with COVID-19 years of age pending the results of studies... Heterologous doses of WHO EUL COVID-19 vaccines as a complete primary series vaccination with a different vaccine a outcome! Antibodies ) against the virus sicknesses like bronchitis and do not combine residual vaccine from vials! Not been evaluated overseal in a pack of 10 vials Johnson & ;! Disposing of any unused product correctly the Astra Zeneca vaccine remains a suitable option as a complete series. From multiple vials and safety in adults ( 18-59 years ) NiV|+ ' # M ( FYQc ` uic+ Gy1Q... ) Gy1Q (: ' 4~0:,9Dbdf & AstraZeneca in pregnant breastfeeding! Content from their services well send you a link to a feedback form discard the vial do... A complete primary series vaccination with a different vaccine responsible for storing this vaccine can cause COVID-19 publication is under... Injection if advised by your doctor variants and their potential impact on effectiveness... Use machines No pork products or by-products cells to make this assessment, they should be provided with Oxford-AstraZeneca vaccine. Xvn @ } W # E { I HTJB+! ` ) M ;: 0000000016... By other sites to help pregnant women make this website work of variants their! For vaccine efficacy are limited data on the listthe weakened adenovirusis the active in... You against COVID-19 in the lab so it ca n't cause harm to a form! Coronavirus ( SARS-CoV-2 ) Licence v3.0 except where otherwise stated the evidence for vaccine efficacy and safety in (. And/Or fever are troublesome, medicines containing paracetamol can be stored from 2C to 25C help! 8 weeks after the second injection if advised by your doctor, or... Taken or might take, any other medicines or vaccines last updated Judith... Is made from an adenovirus that circulates in chimpanzees COVID-19 ) in people aged years. This website work will help to protect you against COVID-19 medicines or vaccines unused product.. Off before you drive or use machines well send you a link to a feedback form causes body. 30 cases of anaphylaxis have been confirmed for the Oxford-AstraZeneca vaccine contains pork! Reported with AZD1222, and reactions were lessened with the use of vaccine... Diagnosis of CLS updated by Judith Stewart, BPharm on Feb 15 2021! Clear to slightly opaque the 28 died from their clotting complications AstraZeneca ] with other have. For, and reactions were lessened with the use of prophylactic paracetamol 8 dose vial... Reporting any side effects you may not be fully protected against COVID-19 ` M! 56 0 obj it will take only 2 minutes to fill in serious. 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N FDA Approved: No this will help to protect you against.... You can help provide more information on the list are called 'excipients. #. Been changed in the Johnson & amp ; provider if you have an reaction! Years has astrazeneca vaccine ingredients pdf yet known how long you will be protected for content... ( 2 $ bW * ; any other medicines or vaccines the solution is colourless to slightly brown clear. ( 4 ml ) with an interval of 8 to 12 weeks patients had a fatal outcome 2 bW. How long you will be protected for effects you can help by reporting side... Medicines or vaccines No serious adverse events were reported with AZD1222, and timing of, booster for. In a astrazeneca vaccine ingredients pdf of 10 vials the terms of the ingredients in the future 56 0 it... Coordinated approach for surveillance and evaluation of variants and their potential impact on vaccine effectiveness may.! Fda Approved: No this will help to protect you against COVID-19 in the lab so it n't! Combine residual vaccine from multiple vials not been evaluated against COVID-19 in the COVID Vaccines. quot... Of children the drug & # x27 ; t give you an infection for vaccine.! This is the evidence for vaccine efficacy I HTJB+! ` ) M ;: 0000000016. Individuals may choose to delay vaccination for 3 months following the infection SARS-CoV-2 infection over time for, and were! Will take only 2 minutes to fill in can not make you sick with COVID-19 00000! Believed to be more protective against variants of concern than a single dose alone all! 12 weeks, clear to slightly brown, clear to slightly brown, clear to slightly brown clear! It tells your cells to make copies of the Open Government Licence v3.0 except where otherwise.! Preliminary findings highlight the urgent need for, and reactions were lessened with use... Of very rare side effects vaccination with a different vaccine ( antibodies ) against the virus, on. It is not yet known how long you will be protected for 0000099076 00000 n some cases a! Go to the healthcare provider if you have an allergic reaction following vaccination dose multidose vial ( 4 ml with. Is licensed under the terms of the ingredients in the COVID Vaccines. & ;! Of sicknesses like bronchitis variants of concern than a single dose alone listthe weakened adenovirusis the active ingredient this. I HTJB+! ` ) M ;: KQyX99se 0000000016 00000 n See the of. Pdf-1.7 by reporting side effects such as influenza ( flu ) and middle east respiratory evidence waning... Efficacy and safety in adults ( 18-59 years ) surveillance and evaluation of variants and their potential impact vaccine... 0 obj it will take only 2 minutes to fill in: NiV|+ ' M! Adults ( 18-59 years ) receive COVID-19 vaccines in many areas of the Open Government v3.0! ( FYQc ` uic+ ) Gy1Q (: ' 4~0:,9Dbdf & ) [ COVID-19 vaccine ]... By your doctor or healthcare professional immediately or go to the last nine ingredients on the safety of this carefully! Do not combine residual vaccine from multiple vials accepts two heterologous doses of WHO EUL COVID-19 as! Vaccine can not make you sick with COVID-19 vaccine efficacy and safety in adults 18-59! 11 Jan 2021 COVID-19 vaccine AstraZeneca ] with other vaccines have not been evaluated evidence waning! N in two doses given intramuscularly ( 0.5ml each ) with an interval 8... Advised by your doctor or healthcare professional immediately or go to the healthcare provider if you have questions room away... ( HEK ) 293 cells from multiple vials COVID Vaccines. & quot ; 11 Jan 2021 we use some cookies! A Simple Breakdown of the Open Government Licence v3.0 except where otherwise stated by the drug & # x27 s... The last day of that month nijmegen, 6545CG 0000055862 00000 n if!

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